Bloomage Biotechnology Corporation Limited（华熙生物科技股份有限公司）is a global leader in the biosynthesis and application of hyaluronic acid and bioactive functional ingredients. Headquartered in Jinan, Shandong Province, China, the company integrates R&D, manufacturing, and commercialization of advanced biomaterials for the medical, cosmetic, nutraceutical, and functional food industries. Bloomage is publicly listed on the Shanghai Stock Exchange (Stock Code: 688363.SH).
Core Business
Bloomage Biotechnology’s core business centers around:
- Fermentation-based production of hyaluronic acid and bioactive ingredients
- Supply of biomaterials for cosmetic, medical aesthetics, functional food, and pharmaceutical applications
- Development of high-value raw materials and branded ingredients for global markets
The company is vertically integrated across the value chain—from microbial fermentation and downstream processing to ingredient branding and market penetration.
Product and Service Offerings
Key product categories include:
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Hyaluronic Acid Series:
- Multiple molecular weights for use in skincare, injectable fillers, dietary supplements, and ophthalmic/orthopedic applications
- Branded products: Hyatrue, Hybloom, miniHA, microHA, Hyacross, cationHA, Hyacolor, HAPLEX
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Recombinant Human Collagen:
- Type I and Type III collagen derived from microbial fermentation
- Used in regenerative medicine, medical dressings, and anti-aging cosmetics
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Gamma-Aminobutyric Acid (GABA):
- Branded as Gabarelax, used in anti-stress nutraceuticals and functional beverages
-
Ergothioneine:
- Antioxidant amino acid sourced from fermentation for skincare and nutritional supplements
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Ectoine:
- Stress-protective molecule for sensitive skin formulations and skin barrier products
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Polydeoxyribonucleotide (PDRN):
- Regenerative nucleotides for advanced skin rejuvenation and wound healing applications
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Pet and Veterinary Ingredients:
- Under the brand HYAPET, including HA-based supplements for joint and skin health in pets
Specialization & Unique Strengths
Bloomage is a world-class specialist in:
- Microbial fermentation technology, being the world’s largest producer of hyaluronic acid by fermentation
- Proprietary multi-grade HA production ranging from 2kDa to 3000kDa molecular weights
- R&D-driven innovation with over 400 patents in bioactive materials and cosmetic applications
- Operation of China's National Hyaluronic Acid Research Center
Their brand portfolio has deep penetration in both B2B and B2C channels, enhancing ingredient awareness and trust.
Financial Overview
As per 2023 financial reports:
- Annual revenue: RMB 5.89 billion (~USD 820 million)
- Net profit: RMB 1.82 billion (~USD 253 million)
- R&D investment: Over RMB 400 million annually
- Revenue breakdown:
- Functional skincare & cosmetics: 55%
- Raw materials & ingredients (HA, collagen, etc.): 35%
- Functional foods and dietary supplements: 10%
The company has shown double-digit growth annually, driven by global demand for biotech-based active ingredients.
Export & Shipment Data
According to export trade platforms:
- Products exported to over 70 countries, including USA, Japan, South Korea, Germany, France, Brazil, and India
- Key international clients include cosmetic giants, pharmaceutical firms, and supplement OEMs
- Over 1,000 shipments annually, mainly through Qingdao and Shanghai Ports
- HA exports branded as HAPLEX® Plus have USP, EP, and JP pharmacopoeia compliance
Bloomage maintains long-term strategic partnerships with top-tier international beauty and wellness brands.
Target Market
Bloomage serves a diversified global client base across industries:
- Cosmetics and skincare OEM/ODM manufacturers
- Medical device and injectable aesthetic companies
- Nutraceutical and functional food brands
- Veterinary nutrition and pet health companies
- Dermatology and aesthetic clinics
The company also supports private label and custom formulation projects for high-growth DTC wellness and beauty startups.
Capabilities
Bloomage operates:
- 6 GMP-certified production plants with capacity for 600 tons/year of HA
- China’s largest fermentation-based biotech platform for collagen, GABA, and active peptides
- CNAS-accredited analytical testing labs
- Fully traceable ERP and MES production systems
- Joint R&D programs with global institutions for efficacy validation and novel bioactive development
Facilities support scalability, pharma-level documentation, and cleanroom compliance.
Certifications & Regulatory Compliance
Bloomage Biotechnology meets global standards including:
- GMP, ISO 9001, ISO 14001, ISO 45001
- FSSC 22000 food safety certification
- FDA DMFs for pharmaceutical-grade HA
- REACH and RoHS compliance for EU markets
- HALAL, KOSHER, Vegan certifications
- China NMPA (formerly CFDA) licensing for medical devices and injectables
Their pharmaceutical-grade HA is registered in the United States, Japan, Korea, EU, and China Drug Master Files.
Customer Testimonials
Industry partners cite:
- Exceptional product quality, purity >99% for HA and GABA
- Batch-to-batch consistency, enabling pharmaceutical and cosmetic applications
- Innovative branded ingredients, enhancing product positioning in crowded categories
- Excellent technical and regulatory support, including clinical documentation
Bloomage's ingredients are widely used in top-selling anti-aging serums, dermal fillers, and joint care supplements.
Major Achievements
- World's largest hyaluronic acid manufacturer by volume
- Listed on Shanghai STAR Market (688363.SH) with market cap exceeding RMB 70 billion
- Developed the first recombinant collagen approved by China's NMPA
- Strategic partnership with L'Oréal, Shiseido, Amorepacific, and P&G
- Featured in Fortune China Top 500 Private Enterprises in Health Sector
- Operates Bloomage Live Beautifully, a consumer brand with strong domestic success
With unmatched fermentation expertise, advanced biotechnology platforms, and global regulatory credentials, Bloomage Biotechnology Corporation Limited continues to lead the global evolution of bioactive ingredients for health, beauty, and longevity.
