Changmao Biochemical Engineering Co., Ltd., headquartered in Changzhou, China, is a globally recognized manufacturer and exporter specializing in the production of organic acids, amino acids, sweeteners, and pharmaceutical intermediates. With a strong commitment to green chemistry and advanced fermentation technology, the company serves a wide range of industries including food, beverage, pharmaceuticals, and fine chemicals.
Company Overview
Founded in 1992, Changmao Biochemical Engineering Co., Ltd. has evolved into one of the world’s largest producers of fumaric acid and malic acid. Listed on the Shenzhen Stock Exchange (Stock Code: 834974), the company operates with a vertically integrated production model, emphasizing quality, sustainability, and continuous innovation.
With more than 30 years of experience in biochemical manufacturing, Changmao has established long-term supply relationships with multinational companies and export operations in over 60 countries worldwide.
Product Portfolio
1. Organic Acids
Changmao’s core competency lies in the production of high-purity organic acids through microbial fermentation and chemical synthesis:
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Fumaric Acid:
- Food-grade and industrial-grade
- Used in beverages, bakery, resin production, and unsaturated polyester
- Global market share: Over 30%
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Malic Acid:
- L-Malic Acid, D-Malic Acid, DL-Malic Acid
- Acidulant in soft drinks, candies, and pharmaceuticals
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Tartaric Acid:
- L(+)-Tartaric Acid, D(-)-Tartaric Acid, DL-Tartaric Acid
- Used in wine stabilization, effervescent tablets, and baking powders
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Maleic Acid:
- Intermediate for coatings, resins, and polymers
2. Amino Acids and Sweeteners
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L-Aspartic Acid:
- Used as a building block for pharmaceuticals and nutritional products
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Aspartame:
- Non-saccharide sweetener used in sugar-free and diet formulations
3. Specialty Chemicals and Pharmaceutical Intermediates
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S(+)-3-Hydroxytetrahydrofuran:
- Chiral intermediate for pharmaceutical synthesis
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Pyrroloquinoline Quinone (PQQ):
- Emerging nutraceutical compound for cognitive and mitochondrial health
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Sodium Pantothenate:
- Vitamin B5 derivative used in food fortification and cosmetics
Manufacturing Capabilities
Changmao operates a state-of-the-art manufacturing complex in Changzhou that includes:
- Fermentation workshops with microbial bioreactors
- Chemical synthesis and purification lines
- Advanced drying, granulation, and packaging facilities
- In-house laboratories for quality control and R&D
Annual production capacities include:
- 30,000+ MT of Fumaric Acid
- 25,000+ MT of Malic Acid (all grades)
- 10,000+ MT of Aspartic Acid
- Export-grade specialty intermediates in metric-ton volumes
Certifications and Compliance
Changmao Biochemical Engineering complies with a comprehensive array of international standards and certifications:
- ISO 9001 – Quality Management System
- ISO 14001 – Environmental Management
- ISO 22000 / HACCP – Food Safety Management
- GMP Certification (for pharmaceutical intermediates)
- Halal and Kosher Certifications
- Products meet FCC, USP, EP, GB standards
Each batch is subject to strict analytical testing, including:
- Heavy metals
- Residual solvents
- Enantiomeric purity
- Microbial contamination
R&D and Innovation
Changmao maintains a national-level research center and collaborates with Chinese and international universities on fermentation optimization, chiral synthesis, and green chemistry processes.
Key achievements:
- More than 40 patents in the field of organic acid biosynthesis
- Proprietary strains and fermentation media formulations for L-malic and L-aspartic acid
- Ongoing innovation in bio-based chemical alternatives for petrochemical derivatives
Global Export and Trade Insights
Changmao is a leading exporter in the biochemical space with well-established logistics infrastructure and regulatory expertise for global trade.
According to trade intelligence platforms:
- Over 3,500 international shipments between 2020 and 2024
- Export destinations include the U.S., Germany, Japan, India, Brazil, South Korea, and Russia
- Key export products: Fumaric acid, L-malic acid, DL-tartaric acid, aspartame
- Average shipment value: $25,000–$80,000 USD per container, depending on product and purity
The company holds REACH registration in Europe and has local distribution agreements in major markets.
Target Industries and Customers
Changmao serves a diverse customer base including:
- Food and beverage manufacturers
- Nutritional supplement producers
- Pharmaceutical companies
- Resin and chemical manufacturers
- Ingredient distributors and trading companies
The company’s product customization, regulatory documentation support, and long shelf-life guarantee enable it to serve both SMEs and multinational corporations.
Competitive Advantages
- One of the world’s top producers of fumaric and malic acid
- Deep vertical integration with control over raw materials, production, and quality
- Global compliance with strict food and pharma-grade certifications
- Flexible production for customized purity levels and granular sizes
- Low environmental footprint and green manufacturing certifications
Industry Recognition
- Awarded National High-Tech Enterprise status in China
- Honored with Green Factory Certification by the Ministry of Industry and Information Technology
- Member of China Food Additives and Ingredients Association (CFAA)
- Regular exhibitor at FIC China, CPhI Worldwide, and IFT Expo USA
Future Strategy
Changmao is investing in:
- Bioplastics and biodegradable intermediates
- Expansion of nutraceutical ingredients portfolio
- AI-assisted fermentation process optimization
- Diversification into precision amino acid derivatives for pharma and biotech
With its proven track record, regulatory foundation, and innovation pipeline, Changmao is poised to remain a global leader in biochemical engineering.
