Founded in 2001, Sichuan Rota Bioengineering Co., Ltd. is a biotechnology-driven manufacturer specializing in the research, development, and large-scale production of bioactive peptides for use in animal health, human healthcare, and biomedical applications. Headquartered in Chengdu, China, Rota Bioengineering is a pioneering innovator in antimicrobial peptides and growth factor peptides, operating under proprietary brands such as Ecotide and Tipek.
Core Business
Rota Bioengineering focuses on the bio-manufacturing of recombinant peptides and proteins using microbial expression systems and proprietary purification techniques. The company supplies high-purity, stable peptide compounds that serve as alternatives to antibiotics, promote growth and immunity, and support gastrointestinal and epithelial health in both animals and humans.
Product and Service Offerings
The company’s core product lines include:
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Antimicrobial Peptides (Ecotide Series)
- Broad-spectrum antimicrobial peptides (AMPs) effective against bacteria, viruses, and fungi
- Used as alternatives to antibiotics in livestock feed and aquaculture
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Epidermal Growth Factor (Tipek)
- Promotes epithelial regeneration and gastrointestinal mucosa protection
- Applied in veterinary medicine, feed additives, and wound healing products
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Trefoil Factor Family Peptides (TFF)
- Gastrointestinal stabilizers that work synergistically with EGF for gut barrier maintenance
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Defensins
- Immunomodulatory peptides used in functional feed additives and biomedical research
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Insulin-like Growth Factors (IGF)
- Supports growth performance and cellular repair processes
All products are manufactured under GMP conditions using bio-fermentation and advanced protein expression systems.
Specialization and Unique Selling Proposition
Rota’s core strength lies in its patented expression platforms for recombinant peptide synthesis, enabling:
- High bioactivity retention through precise folding and purification techniques
- Scalability for both pilot and industrial-scale production
- Cost-effective and antibiotic-free feed additive solutions
- Enhanced peptide stability in high-temperature pelleting conditions
- Custom peptide design services based on customer R&D needs
The company's focus on post-antibiotic era solutions makes it a front-runner in sustainable animal nutrition and pharmaceutical peptide development.
Financial Performance
Based on industry analytics and company disclosures:
- Estimated Annual Revenue: $12–18 million USD
- Export Revenue Share: Approx. 50%
- R&D Investment: More than 10% of annual revenue
- Production Capacity: 120+ metric tons/year of recombinant peptides
The company’s revenue is driven by both product sales and strategic licensing of peptide technologies to partners in Europe and Asia.
International Shipments & Market Footprint
According to trade intelligence from platforms such as ImportYeti and customs reports:
- Over 1,000 international shipments since 2016
- Export destinations include: Vietnam, India, Thailand, Indonesia, South Korea, and Germany
- Key export products: Ecotide series, Tipek (EGF), and recombinant TFF peptides
The company has established long-term collaborations with global feed premix manufacturers, animal health product distributors, and biomedical research firms.
Target Markets
Rota Bioengineering’s products are used in:
- Livestock and aquaculture feed premixes
- Veterinary medicine formulations
- Functional foods and nutraceuticals
- Biomedical and pharmaceutical R&D
- Cell culture and wound healing formulations
Their client base includes multinational animal nutrition companies, research labs, and biotech startups.
Capabilities
- GMP-certified fermentation and purification facility
- Proprietary microbial expression platforms (E. coli, yeast)
- Advanced chromatography, lyophilization, and encapsulation capabilities
- In-house R&D for novel peptide design, stability testing, and field trials
- Technical and regulatory support for product registration in global markets
Rota also supports custom development projects, from sequence optimization to scale-up and commercialization.
Certifications and Compliance
- GMP-certified production site
- ISO 9001:2015 Quality Management System
- Products tested in accordance with China Veterinary Drug Administration standards
- Export-ready documentation including COA, MSDS, and bioactivity reports
- Ongoing R&D collaborations with top Chinese and international research institutes
Regulatory support is provided for compliance with feed additive guidelines in Asia, EU, and LATAM markets.
Customer Testimonials
“We’ve been using Ecotide in our antibiotic-free broiler program. Improved gut health and lower mortality were evident within 30 days.”
— Director of Nutrition, Poultry Integrator, Vietnam
“Tipek is an exceptional mucosal repair agent. We use it in our aquafeed formulations to reduce gut stress in high-density systems.”
— Product Manager, Aquafeed Company, Thailand
Major Achievements
- Filed over 20 patents related to recombinant peptide expression and stabilization
- Recognized as a National High-Tech Enterprise by China’s Ministry of Science and Technology
- Participated in international expos including VIV Asia, IPPE, and BioChina
- Collaborated with Chinese Academy of Agricultural Sciences (CAAS) on gut immunity research
- Developed custom AMPs for two leading EU veterinary pharmaceutical companies
With its unique peptide technology platform, scalable production, and commitment to antibiotic-free innovation, Sichuan Rota Bioengineering Co., Ltd. continues to be a vital player in advancing bioactive peptides for sustainable animal health and next-generation life sciences.