Beijing Refine Biology Co., Ltd. (北京瑞芬生物科技股份有限公司) is a prominent Chinese biotechnology company focused on the development, production, and export of natural plant-based ingredients and functional systems for the global food, beverage, nutraceutical, and pharmaceutical markets. Headquartered in Beijing, China, the company operates under the brand Refine Biology and is recognized for its scientific innovation in natural sweeteners, botanical extracts, and customized formulation systems.
Core Business and Product Portfolio
Refine Biology delivers high-value ingredients organized under four strategic product categories, catering to clean-label, health-focused, and plant-based market trends.
1. Refine Sweet
- A portfolio of natural high-intensity sweeteners developed from plant sources:
- Monk Fruit Extract (Mogroside V >50%)
- Stevia Extract (Rebaudioside A, D, M)
- Used as sugar substitutes in:
- Functional beverages
- Bakery products
- Low-calorie snacks and confectionery
- All sweeteners are:
- Non-GMO
- GRAS-certified
- Free from synthetic additives
2. Refine Natural
- A range of botanical functional ingredients with targeted health benefits:
- Ginseng Extract – Adaptogenic benefits, rich in ginsenosides
- Bilberry Extract – Vision and antioxidant support
- Goji Berry Extract, Elderberry Extract, and others
- Applications include:
- Dietary supplements
- Fortified beverages
- Functional foods
3. Refine Nacolor
- Natural colorants derived from plant and fruit sources
- Anthocyanins, carotenoids, chlorophyll derivatives
- Compliant with EU and FDA food color regulations
- Used in:
- Yogurts, beverages, candy, and natural skincare
- Known for high stability and excellent water solubility
4. Refine System
- Tailor-made formulation solutions developed to meet customer-specific application needs:
- Sweetener blends with bulking agents
- Nutrient systems with vitamins and herbal actives
- Flavored and colored natural ingredient systems
- Supports clients in rapid product development and clean-label reformulation
Manufacturing Capabilities and Infrastructure
Refine Biology operates GMP-certified production facilities equipped with:
- CO₂ supercritical extraction systems
- Spray-drying and membrane concentration units
- Automated blending and filling lines
The company ensures complete vertical integration from raw material sourcing to final product packaging, with:
- Annual extraction capacity of 1,200+ tons of raw botanicals
- In-house analytical lab equipped with HPLC, UV, GC, and microbial testing
All products are subjected to multi-stage quality control protocols, ensuring compliance with global food and supplement safety standards.
Export Activity and Global Market Presence
Beijing Refine Biology exports its products to more than 40 countries, including:
- United States, Canada, Germany, Japan, South Korea, Australia, and UAE
Trade insights from industry platforms show:
- Over 150 international consignments completed in the last 3 years
- Key exports include monk fruit extract and natural color systems
- Shipment values range from USD 20,000 to 100,000 per order, depending on product type and volume
The company maintains long-term partnerships with:
- Functional food brands
- Nutraceutical companies
- Ingredient distributors
Certifications and Quality Standards
Refine Biology ensures global regulatory readiness through:
- ISO 9001:2015 Quality Management System
- ISO 22000:2018 Food Safety Certification
- HACCP
- Halal and Kosher Certifications
- FDA GRAS Notification for monk fruit extract and stevia
All products meet the standards of Chinese Pharmacopoeia, USP, and EP, with full traceability documentation.
Research and Development
With a strong commitment to innovation, Refine Biology operates an in-house R&D and Innovation Center in Beijing, supported by partnerships with:
- Chinese Academy of Agricultural Sciences
- Beijing University of Chinese Medicine
Key R&D initiatives include:
- High-purity extraction technologies
- Improved flavor modulation of natural sweeteners
- Stability enhancement of natural colorants under processing conditions
- Sugar-reduction systems for beverages and baked goods
The R&D team supports custom formulation projects and rapid prototyping for client brands.
Target Customers and Industry Applications
Refine Biology’s product portfolio is designed for:
- Functional food and beverage manufacturers
- Dietary supplement producers
- Natural colorant and sweetener distributors
- Private label nutrition brands
Their flexible business model supports:
- Bulk ingredient supply
- OEM/ODM services
- Regulatory and technical documentation
Competitive Advantages
- Specialized in plant-derived functional ingredients
- Vertically integrated operations from raw material sourcing to finished product
- Strong focus on clean-label, non-GMO, and health-enhancing formulations
- Technical expertise in customized ingredient systems
- Reliable and compliant international shipping and documentation
Achievements and Recognition
- Recognized as a "High-Tech Enterprise of Beijing Municipality"
- Awarded for innovation in sugar reduction technology
- Approved supplier to top-tier functional food and beverage companies in North America and Europe
- Participated in major industry events such as FI Asia, Vitafoods Europe, and SupplySide West
Beijing Refine Biology Co., Ltd. continues to expand its global presence as a trusted, science-driven partner for natural ingredient solutions, enabling food and health companies to meet the rising demand for wellness, functionality, and transparency in their products.
