Ningxia Qiyuan Pharmaceutical Co., Ltd. is a leading Chinese manufacturer of active pharmaceutical ingredients (APIs), specializing in antibiotic and vitamin compounds for global pharmaceutical markets. Headquartered in Yinchuan, Ningxia Hui Autonomous Region, China, the company has emerged as a major supplier of macrolide and tetracycline-based APIs and intermediates. With a vertically integrated production system, robust R&D capabilities, and international GMP compliance, Qiyuan Pharma supplies to clients in over 40 countries.
Company Background
Founded in 2001, Ningxia Qiyuan Pharmaceutical originated from a restructuring of a state-owned chemical enterprise. Over the past two decades, it has developed into a high-tech, GMP-compliant pharmaceutical company operating on more than 259,740 square meters of land. It employs over 1,000 staff, including experienced professionals in R&D, quality control, production, and international trade.
Qiyuan Pharma operates under the "Qiyuan" brand and holds multiple manufacturing licenses for antibiotic and vitamin APIs. The company integrates fermentation, synthesis, purification, and drying technologies across multiple production lines.
Core Business
Ningxia Qiyuan’s main business involves:
- Production of macrolide and tetracycline antibiotic APIs
- Manufacturing of vitamin C (ascorbic acid) and intermediates
- Global supply of pharmaceutical intermediates
- Contract manufacturing and export services
Its products serve pharmaceutical formulation manufacturers, bulk drug distributors, and contract development organizations across Asia, Europe, South America, and the Middle East.
Product & Service Offerings
Antibiotic APIs
- Erythromycin Base
- Erythromycin Thiocyanate
- Azithromycin
- Clarithromycin
- Tetracycline Base
- Tetracycline Hydrochloride
Vitamin APIs & Intermediates
- Ascorbic Acid (Vitamin C)
- 2-Keto-L-Gulonic Acid – key intermediate for vitamin C synthesis
Other Pharmaceutical Ingredients
- Avermectin – a widely used antiparasitic compound
Services
- Custom synthesis and contract manufacturing
- Export registration support and documentation
- Full-spectrum QC testing (HPLC, GC, UV, microbiology)
- Pharmacopoeial standard compliance: USP, EP, ChP
Specialization and Unique Strengths
- One of China's few tetracycline base API producers
- Advanced Fermentation Facilities: Large-scale microbial fermentation capabilities for antibiotic precursors
- Regulatory Filing Experience: Products registered in 10+ countries with DMFs available
- Strong Technical Expertise: Over 100 R&D and QA professionals
- Integrated Production Lines: Control from fermentation to final packaging ensures traceability and purity
Financial Insights
Ningxia Qiyuan Pharma, though privately held, demonstrates high-capacity manufacturing and export volumes that reflect strong financial performance:
- Estimated Revenue: USD $40–60 million annually
- Production Capacity:
- Erythromycin: >2,000 MT/year
- Tetracycline: >1,000 MT/year
- Ascorbic Acid: >3,000 MT/year
- R&D Investment: Over USD $2 million annually into process improvement and new drug development
- Export Ratio: Over 60% of total production is exported
Export and Shipment Records
- Active exports to India, Brazil, Russia, Pakistan, Bangladesh, Egypt, and EU countries
- Regular presence on B2B platforms such as CPHI Online, PharmaCompass, LookChem
- API shipments compliant with global GMP and local regulatory requirements
- Export documentation includes: DMF, CoA, GMP certificate, MSDS, TDS
Target Market
- Generic Drug Manufacturers
- Pharmaceutical Bulk Buyers and Traders
- Contract Development and Manufacturing Organizations (CDMOs)
- API Distributors
- Veterinary API Buyers
Capabilities
- Area: Over 259,000 m² (production + warehouse + office + utilities)
- Staff: Over 1,000 employees
- Facilities:
- Fermentation workshops
- Chemical synthesis reactors
- Purification columns and crystallization tanks
- GMP-grade clean rooms
- QC Laboratories: Equipped with HPLC, GC, UV spectrophotometers, and microbial testing suites
- Waste Management: On-site wastewater treatment and solid waste neutralization systems
Certifications and Compliance
- China GMP Certified
- DMFs Filed in Multiple Markets
- ISO 9001:2015 – Quality Management
- ISO 14001 – Environmental Management
- Occupational Safety Compliance
- Halal and Kosher Available (Product Specific)
Customer Testimonials
"We have sourced erythromycin thiocyanate and azithromycin from Qiyuan for over four years. Their product stability and regulatory support have enabled us to launch several finished formulations in Latin America."
— Regulatory Affairs Manager, South American Pharma Group
"Qiyuan is one of the few API manufacturers that could meet both our volume and pharmacopoeial compliance needs. Their ascorbic acid has proven excellent in terms of assay and impurity profile."
— Quality Head, Indian Generic Pharma Company
Achievements
- One of China’s top exporters of macrolide and tetracycline APIs
- Recognized as a High-Tech Enterprise in Ningxia Hui Autonomous Region
- Successfully supported ANDA filings for multiple overseas customers
- Expanded production facility by 30% capacity between 2020–2023
- Long-standing partnerships with multinational buyers in India, Brazil, and Eastern Europe
